4 days in Amsterdam, Brussels & Luxembourg City Itinerary

Created using Inspirock Europe itinerary planner
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Drive
1
Amsterdam, The Netherlands
— 2 nights
Drive
2
Brussels, Belgium
— 1 night
Drive
3
Luxembourg City, Luxembourg
— 1 day
Drive

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Amsterdam, The Netherlands — 2 nights

Venice of the North

Known as one of the greatest small cities in the world, Amsterdam charms visitors with its cool and cozy atmosphere.
Kick off your visit on the 13th (Thu): admire the masterpieces at Van Gogh Museum, walk around Vondelpark, then examine the collection at Anne Frank House, and finally get to know the fascinating history of Begijnhof. Keep things going the next day: admire the masterpieces at Rijksmuseum, explore the world behind art at Stedelijk Museum Amsterdam, and then take in nature's colorful creations at Keukenhof.

For traveler tips, more things to do, photos, and more tourist information, you can read our Amsterdam trip itinerary planner.

Frankfurt, Germany to Amsterdam is an approximately 4.5-hour car ride. You can also fly; or do a combination of train and flight. April in Amsterdam sees daily highs of 15°C and lows of 5°C at night. Finish your sightseeing early on the 15th (Sat) to allow enough time to drive to Brussels.
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Museums · Parks · Historic Sites
Side Trip
Find places to stay Apr 13 — 15:

Brussels, Belgium — 1 night

Capital of Europe

The allure of the multi-cultural capital, Brussels, stems from its mix of political intrigue, artistic influence, historical significance, and a thriving social scene.
Start off your visit on the 15th (Sat): contemplate in the serene atmosphere at St. Michael and St. Gudula Cathedral (Cathedrale St-Michel et Ste-Gudule), make a trip to Grand Place, then pause for some photo ops at Manneken Pis, then examine the collection at Belgian Comic Strip Center, and finally examine the collection at Atomium.

To see maps, photos, more things to do, and more tourist information, you can read our Brussels route maker website.

Traveling by car from Amsterdam to Brussels takes 2.5 hours. Alternatively, you can take a train; or fly. In April, daily temperatures in Brussels can reach 15°C, while at night they dip to 4°C. Finish up your sightseeing early on the 16th (Sun) so you can go by car to Luxembourg City.
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Museums · Historic Sites
Find places to stay Apr 15 — 16:

Luxembourg City, Luxembourg — 1 day

Gibraltar of the North

While Luxembourg City boasts the shiny headquarters of several European institutions and EU offices, it is also home to a beautiful old town that's designated as a World Heritage Site.
Start off your visit on the 16th (Sun): don't miss a visit to William Square, take in the architecture and atmosphere at Cathedrale Notre-Dame, explore the historical opulence of Grand Ducal Palace, then take an in-depth tour of Letzebuerg City Museum, then get to know the fascinating history of Le Chemin de la Corniche, and finally explore the striking landscape at Casemates du Bock.

To find ratings, reviews, and tourist information, use the Luxembourg City online trip itinerary builder.

You can drive from Brussels to Luxembourg City in 2.5 hours. Other options are to take a bus; or take a train. April in Luxembourg City sees daily highs of 15°C and lows of 5°C at night. Cap off your sightseeing on the 16th (Sun) early enough to go by car back home.
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Historic Sites · Museums · Parks · Nature
Find places to stay Apr 16 — 17: