51 days in Guatemala, Nicaragua & Panama Itinerary

51 days in Guatemala, Nicaragua & Panama Itinerary

Created using Inspirock Central America travel route planner

This plan was created by another user. Make it your plan

Route & dates

Start: Tulum, Mexico
+2
Drive + Fly + Drive:  16 h 45 min
1
Tikal National Park, Guatemala
— 1 night
Drive:  8 h 15 min
2
Lanquin, Guatemala
— 1 night
Drive:  5 h 15 min
3
Antigua, Guatemala
— 9 nights
Drive:  2 h 30 min
4
San Lucas Toliman, Guatemala
— 1 night
+2
Drive + Fly + Drive:  9 h
5
Leon, Nicaragua
— 3 nights
Drive:  2 h 15 min
6
Granada, Nicaragua
— 3 nights
Drive:  1 h 45 min
7
San Juan del Sur, Nicaragua
— 4 nights
Drive:  2 h 30 min
8
Isla de Ometepe, Nicaragua
— 4 nights
Fly:  11 h 15 min
9
Big Corn Island, Nicaragua
— 3 nights
Fly:  17 h 15 min
10
Panama City, Panama
— 5 nights
Bus:  1 h 15 min
11
Colon, Panama
— 3 nights
Bus + Fly:  2 h 30 min
12
Bocas Town, Panama
— 3 nights
Drive:  4 h 45 min
13
Boquete, Panama
— 4 nights
Drive + Ferry:  3 h 45 min
14
Isla Bastimentos, Panama
— 2 nights
Ferry + Drive:  1 h
15
Bluff Beach, Panama
— 1 night
+2
Taxi + Ferry + Bus:  1 h 45 min
16
Changuinola, Panama
— 1 night
Fly + Drive:  16 h 45 min
End: Puerto Colombia, Colombia

1
night
Tikal National Park, Guatemala

Tikal National Park
Take a trip to Tikal National Park and discover an ancient city in the thick tropical jungle.
Kick off your visit on the 13th (Wed): see the interesting displays at Centro de Conservacion e Investigaction.

For ratings, more things to do, maps, and other tourist information, read Tikal National Park day trip planning app.

Tulum, Mexico to Tikal National Park is an approximately 17- hour combination of car and flight. The time zone difference when traveling from Tulum to Tikal National Park is minus 1 hour. You'll have a few hours on the 13th (Wed) to wrap things up before traveling to Lanquin.

Things to do in Tikal National Park

Museums
Find places to stay Nov 12 — 13:

1
night
Lanquin, Guatemala

Lanquin ©
San Agustín Lanquín, often referred to simply as Lanquín, is a municipality in the Guatemalan department of Alta Verapaz. Kick off your visit on the 14th (Thu): explore the striking landscape of Parque Nacional Grutas de Lanquin and then admire the sheer force of Monumento Natural Semuc Champey.

To see ratings, maps, photos, and other tourist information, you can read our Lanquin route builder.

You can drive from Tikal National Park to Lanquin in 8.5 hours. Other options are to do a combination of bus and shuttle; or take a bus. In November, plan for daily highs up to 36°C, and evening lows to 25°C. Wrap up your sightseeing by early afternoon on the 14th (Thu) to allow enough time to drive to Antigua.

Things to do in Lanquin

Nature Parks

Side Trip

Parque Nacional Grutas de Lanquin
Find places to stay Nov 13 — 14:
Highlights from your plan
Monumento Natural Semuc Champey ©
Monumento Natural Semuc Champey
Parque Nacional Grutas de Lanquin
Parque Nacional Grutas de Lanquin

9
nights
Antigua, Guatemala

Antigua ©
The former capital of Guatemala and a World Heritage Site, Antigua retains its colonial charm and remains one of the most visited destinations in the country.
Venture out of the city with trips to Iximche (in Panajachel), Guatemala City (La Aurora Zoo, Palacio Nacional, &more) and Santo Tomas Church (in Chichicastenango). And it doesn't end there: get impressive views of Volcán Pacaya, examine the collection at ChocoMuseo, make a trip to The Plaza Central Park, and explore the ancient world of Convento de las Capuchinas.

To see other places to visit, photos, maps, and tourist information, read our Antigua trip itinerary planning website.

Getting from Lanquin to Antigua by car takes about 5.5 hours. Other options: take a shuttle; or take a bus. Expect slightly colder temperatures when traveling from Lanquin in November; daily highs in Antigua reach 27°C and lows reach 17°C. Wrap up your sightseeing on the 23rd (Sat) to allow time to travel to San Lucas Toliman.

Things to do in Antigua

Historic Sites Museums Parks

Side Trips

Guatemala City, Iximche, Santo Tomas Church
Find places to stay Nov 14 — 23:
Highlights from your plan
Arco de Santa Catalina ©
Arco de Santa Catalina
Volcán Pacaya ©
Volcán Pacaya
Cerro de la Cruz ©
Cerro de la Cruz

1
night
San Lucas Toliman, Guatemala

San Lucas Toliman ©
San Lucas Tolimán is a municipality in the Sololá department of Guatemala. On the 24th (Sun), contemplate the waterfront views at Lake Atitlan, take in the spiritual surroundings of Colonial Church, and then examine the collection at Cojolya Museum and Store. Here are some ideas for day two: get impressive views of Volcan Atitlan.

To find where to stay, reviews, and more tourist information, read our San Lucas Toliman holiday website.

Drive from Antigua to San Lucas Toliman in 2.5 hours. Expect a daytime high around 27°C in November, and nighttime lows around 17°C. On the 25th (Mon), wrap the sightseeing up by early afternoon so you can travel to Leon.

Things to do in San Lucas Toliman

Nature Parks Museums

Side Trips

Santiago Atitlan, Lake Atitlan
Find places to stay Nov 23 — 25:
Highlights from your plan
Lake Atitlan ©
Lake Atitlan
Volcan Atitlan ©
Volcan Atitlan
Colonial Church ©
Colonial Church

3
nights
Leon, Nicaragua

Leon ©
A cultured and storied city, Leon attracts guests from all over the world, drawn to the second city's style, thriving intellectual life, and liveliness.
Leon is known for nature, museums, and beaches. Your plan includes some of its best attractions: contemplate the geological forces at Cerro Negro Volcano, look for gifts at Juanmarcos Design, enjoy the sand and surf at Playa Las Penitas, and stop by Catedral de la Asunción.

To see traveler tips, where to stay, ratings, and tourist information, read Leon online trip maker.

Use the Route module to find suitable travel options from San Lucas Toliman to Leon. In November, Leon is somewhat warmer than San Lucas Toliman - with highs of 37°C and lows of 27°C. Cap off your sightseeing on the 28th (Thu) early enough to go by car to Granada.

Things to do in Leon

Parks Nature Museums
Find places to stay Nov 25 — 28:
Highlights from your plan
Cerro Negro Volcano ©
Cerro Negro Volcano
Museo de Arte Fundacion Ortiz-Gurdian ©
Museo de Arte Fundacion Ortiz-Gurdian
Telica Volcano ©
Telica Volcano

3
nights
Granada, Nicaragua

Granada
The lakeside city of Granada has the look and feel of a historically important economic and political center, with grand colonial architecture, a unified look, and many cultural attractions.
Explore Granada's surroundings by going to Apoyo (in La Laguna de Apoyo), Managua (Puerto Salvador Allende & Mercado Roberto Huembes) and Masaya Volcano (in Masaya). The adventure continues: head off the coast to Islets of Granada, take in the architecture and atmosphere at Iglesia de La Merced, don't miss a visit to Parque Xalteva, and steep yourself in history at Palacio Episcopal.

To find maps, traveler tips, and tourist information, go to the Granada visit planner.

Traveling by car from Leon to Granada takes 2.5 hours. Alternatively, you can take a shuttle; or take a bus. Cap off your sightseeing on the 1st (Sun) early enough to go by car to San Juan del Sur.

Things to do in Granada

Nature Parks Historic Sites

Side Trips

Managua, Masaya
Find places to stay Nov 28 — Dec 1:
Highlights from your plan
Apoyo
Apoyo
Islets of Granada ©
Islets of Granada
Iglesia de La Merced ©
Iglesia de La Merced

4
nights
San Juan del Sur, Nicaragua

Set in a crescent-shaped bay, San Juan del Sur has become known as a popular surfing spot and coastal holiday destination for Nicaraguan families and international visitors alike.
San Juan del Sur is known for adventure, beaches, and spas. Your plan includes some of its best attractions: enjoy the sand and surf at La Flor Beach Natural Reserve, get outside with Da' Flying Frog Extreme Adventure, get your game on at Surf Ranch Skateboard Park, and don't miss a visit to Mirador del Cristo de la Misericordia.

To find reviews, photos, where to stay, and tourist information, refer to the San Juan del Sur day trip website.

Drive from Granada to San Juan del Sur in 2 hours. Alternatively, you can do a combination of shuttle and bus; or take a shuttle. December in San Juan del Sur sees daily highs of 34°C and lows of 28°C at night. Wrap up your sightseeing on the 5th (Thu) early enough to drive to Isla de Ometepe.

Things to do in San Juan del Sur

Outdoors Parks Beaches
Find places to stay Dec 1 — 5:
Highlights from your plan
Zipline
La Flor Beach Natural Reserve ©
La Flor Beach Natural Reserve
Mirador del Cristo de la Misericordia ©
Mirador del Cristo de la Misericordia

4
nights
Isla de Ometepe, Nicaragua

Isla de Ometepe
Isla de Ometepe may be small in size, but it boasts two large volcanoes that dominate its landscape and influence the local lifestyle.
Isla de Ometepe is known for nature, beaches, and museums. Your plan includes some of its best attractions: contemplate the waterfront views at Laguna Charco Verde, contemplate the geological forces at Volcan Concepcion, see the interesting displays at El Ceibo Museums, and step off the mainland to explore Isla Ometepe.

Start your trip to Isla de Ometepe by creating a personalized itinerary on Inspirock.

Traveling by car from San Juan del Sur to Isla de Ometepe takes 2.5 hours. Cap off your sightseeing on the 9th (Mon) early enough to catch the flight to Big Corn Island.

Things to do in Isla de Ometepe

Nature Parks Theme Parks
Find places to stay Dec 4 — 9:
Highlights from your plan
Isla Ometepe
Isla Ometepe
Laguna Charco Verde ©
Laguna Charco Verde
Volcan Concepcion ©
Volcan Concepcion

3
nights
Big Corn Island, Nicaragua

The larger of the two islands, Big Corn Island offers a laid-back atmosphere and tropical island scenery.
Big Corn Island is known for wildlife, nature, and adventure. Your plan includes some of its best attractions: take a memorable tour with Tours and step off the mainland to explore nautilus corn island.

To find more things to do, ratings, other places to visit, and tourist information, you can read our Big Corn Island road trip app.

You can fly from Isla de Ometepe to Big Corn Island in 11.5 hours. Alternatively, you can ride a ferry; or do a combination of bus, taxi, and ferry. In December in Big Corn Island, expect temperatures between 34°C during the day and 28°C at night. On the 12th (Thu), you're off to Panama City.

Things to do in Big Corn Island

Wildlife Tours Outdoors
Find places to stay Dec 9 — 12:
Highlights from your plan
Scuba & Snorkeling
nautilus corn island ©
nautilus corn island

5
nights
Panama City, Panama

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Panama City is known for historic sites, shopping, and museums. Your plan includes some of its best attractions: don't miss a visit to Amador Causeway (Calzada de Amador), stop by Cinta Costera, get to know the fascinating history of Avenida Balboa, and get engrossed in the history at Museo del Canal Interoceanico de Panama.

To find ratings, maps, more things to do, and other tourist information, use the Panama City holiday planner.

The Route module can help you plan travel from Big Corn Island to Panama City. The time zone changes from Central Standard Time (CST) to Eastern Standard Time (EST), which is usually a 1 hour difference. In December in Panama City, expect temperatures between 36°C during the day and 28°C at night. Cap off your sightseeing on the 17th (Tue) early enough to catch the bus to Colon.

Things to do in Panama City

Historic Sites Neighborhoods Shopping
Find places to stay Dec 12 — 17:
Highlights from your plan
Panama Canal ©
Panama Canal
Amador Causeway (Calzada de Amador) ©
Amador Causeway (Calzada de Amador)
Casco Viejo ©
Casco Viejo

3
nights
Colon, Panama

Colon ©
Founded in the 1850s by Americans building the country's first railroad, Colon is now one of the largest duty-free ports in the world.
Explore the numerous day-trip ideas around Colon: Portobelo (Safarick's Zoologico - Animal Rescue & Rehabilitation, Museo de La Real Aduana de Portobelo, &more). The adventure continues: don't miss a visit to Gatun Locks, take in panoramic vistas at Observation Centre Canal Expansion, stop by Panamá-Canal Railroad, and take in the spiritual surroundings of Iglesia de Cristo a Orillas del Mar.

To find maps, ratings, other places to visit, and more tourist information, use the Colon online sightseeing planner.

Traveling by bus from Panama City to Colon takes 1.5 hours. Alternatively, you can drive. Finish your sightseeing early on the 20th (Fri) to allow enough time to travel to Bocas Town.

Things to do in Colon

Historic Sites Wildlife Tours

Side Trip

Portobelo
Find places to stay Dec 17 — 20:
Highlights from your plan
Fort San Lorenzo ©
Fort San Lorenzo
Gatun Locks
Gatun Locks
Museo de La Real Aduana de Portobelo ©
Museo de La Real Aduana de Portobelo

3
nights
Bocas Town, Panama

The colorful and relaxed Bocas Town has a welcoming atmosphere, with the modestly sized urban area showcasing typical Caribbean clapboard houses and home to a mixed community from across the world.
Bocas Town is known for wildlife, beaches, and outdoors. Your plan includes some of its best attractions: see some colorful creatures with a scuba or snorkeling tour, stop by Up In The Hill, stroll through Dolphin Bay Preserve, and kick back and relax at Boca del Drago.

For photos, ratings, other places to visit, and other tourist information, read our Bocas Town trip itinerary maker app.

Do a combination of bus and flight from Colon to Bocas Town in 2.5 hours. Alternatively, you can do a combination of bus and ferry. Expect a daytime high around 30°C in December, and nighttime lows around 30°C. Wrap up your sightseeing on the 23rd (Mon) to allow time to drive to Boquete.

Things to do in Bocas Town

Parks Outdoors Beaches

Side Trips

Finca Los Monos Botanical Garden, Up In The Hill
Find places to stay Dec 20 — 23:
Highlights from your plan
Scuba & Snorkeling
Starfish Beach
Starfish Beach
Boca del Drago ©
Boca del Drago

4
nights
Boquete, Panama

Boquete ©
Now known internationally for its fresh mountain air, year-round pleasant temperatures, and large community of North American expats, Boquete has changed rapidly since the start of the century, changing from a humble mountain town, into a humble mountain surrounded by gated communities and estates.
Boquete is known for adventure, nature, and spas. Your plan includes some of its best attractions: contemplate the geological forces at Volcan Baru National Park, indulge in some personalized pampering at some of the best spas, hike along Sendero Los Quetzales (The Quetzales Trail), and relax in the rural setting at Boquete Bees.

For more things to do, other places to visit, photos, and tourist information, use the Boquete trip planner.

You can drive from Bocas Town to Boquete in 5 hours. Finish your sightseeing early on the 27th (Fri) so you can travel to Isla Bastimentos.

Things to do in Boquete

Parks Outdoors Tours
Find places to stay Dec 23 — 27:
Highlights from your plan
Volcan Baru National Park ©
Volcan Baru National Park
Sendero Los Quetzales (The Quetzales Trail) ©
Sendero Los Quetzales (The Quetzales Trail)
Boquete Bees ©
Boquete Bees

2
nights
Isla Bastimentos, Panama

Isla Bastimentos ©
Sitting fairly close to the mainland and just a short boat ride from Bocas del Toro International Airport, the well-connected but still preserved Isla Bastimentos offers access to a national park of protected rainforest and coastline, as well as an abundance of small, uninhabited islands dotted just offshore.
Kick off your visit on the 28th (Sat): step off the mainland to explore Isla Bastimentos and then stroll through Polo Beach. Get ready for a full day of sightseeing on the 29th (Sun): stroll through Wizard Beach and then enjoy the sand and surf at Red Frog Beach.

To see more things to do, other places to visit, maps, and other tourist information, you can read our Isla Bastimentos trip planner.

Traveling by combination of car and ferry from Boquete to Isla Bastimentos takes 4 hours. Alternatively, you can do a combination of bus and ferry. In December, daytime highs in Isla Bastimentos are 30°C, while nighttime lows are 30°C. Wrap up your sightseeing on the 29th (Sun) early enough to travel to Bluff Beach.

Things to do in Isla Bastimentos

Parks Outdoors Beaches
Find places to stay Dec 27 — 29:
Highlights from your plan
Red Frog Beach ©
Red Frog Beach
Isla Bastimentos ©
Isla Bastimentos
Wizard Beach ©
Wizard Beach

1
night
Bluff Beach, Panama

Bluff Beach ©
On the 30th (Mon), tour the pleasant surroundings at Bocas Butterfly Garden and then don't miss a visit to Playa Bluff.

Plan my day in Bluff Beach using traveler tips and tourist information provided by Inspirock.

Traveling by combination of ferry and car from Isla Bastimentos to Bluff Beach takes an hour. Expect a daytime high around 30°C in December, and nighttime lows around 30°C. Finish your sightseeing early on the 30th (Mon) so you can travel to Changuinola.

Things to do in Bluff Beach

Wildlife Parks

Side Trip

Bocas Butterfly Garden
Find places to stay Dec 29 — 30:
Highlights from your plan
Playa Bluff ©
Playa Bluff

1
night
Changuinola, Panama

Changuinola ©
Changuinola is a city in the Bocas del Toro Province of Panama and seat city of the Changuinola District. On the 31st (Tue), get outside with Aamvecona.

For where to stay, more things to do, and more tourist information, refer to the Changuinola trip itinerary maker app.

Traveling by combination of taxi, ferry, and bus from Bluff Beach to Changuinola takes 2 hours. On the 31st (Tue), wrap the sightseeing up by early afternoon so you can travel back home.

Things to do in Changuinola

Outdoors
Find places to stay Dec 30 — 31:
Highlights from your plan
Aamvecona ©
Aamvecona

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